Provided is a wear-resistant structure for a laterite nickel ore autoclave. The wear-resistant structure for the laterite nickel ore autoclave includes an autoclave body, an insulation sleeve, and a wear-resistant plate. The autoclave body has an accommodating cavity, and a first mounting groove is disposed on an inner wall of the accommodating cavity. The insulation sleeve is embedded in the first mounting groove and provided with a second mounting groove. The wear-resistant plate is embedded in the second mounting groove, where the insulation sleeve is used for blocking a charge flow between the wear-resistant plate and the autoclave body. The insulation sleeve is embedded in the first mounting groove, and the wear-resistant plate is embedded in the second mounting groove. In this case, the wear-resistant plate can be secured in the autoclave body. Therefore, the wear resistance of the stirring region can be improved by using the wear-resistant plate. Moreover, the insulation sleeve can block the charge flow between the wear-resistant plate and the autoclave body, thereby blocking the galvanic cell effect between the wear-resistant plate and the autoclave body, avoiding the problem that the corrosion speed of the autoclave body is accelerated due to the galvanic cell effect caused by different types of metals, and prolonging the service life of the autoclave.